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Variations in the TNFα gene and their interactions with the IL4R and IL10 genes in relation to hand osteoarthritis

BACKGROUND: The development of osteoarthritis (OA) involves inflammation, but the evidence for participation of genes propagating or inhibiting inflammation in the OA process is inconsistent. We investigated the associations of common variants in the TNFα gene, and their interactions with other cyto...

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Detalles Bibliográficos
Autores principales: Hämäläinen, Satu, Solovieva, Svetlana, Vehmas, Tapio, Leino-Arjas, Päivi, Hirvonen, Ari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4181701/
https://www.ncbi.nlm.nih.gov/pubmed/25252624
http://dx.doi.org/10.1186/1471-2474-15-311