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Integrated genomic study of quadruple-WT GIST (KIT/PDGFRA/SDH/RAS pathway wild-type GIST)

BACKGROUND: About 10-15% of adult gastrointestinal stromal tumors (GIST) and the vast majority of pediatric GIST do not harbour KIT or platelet-derived growth factor receptor alpha (PDGFRA) mutations (J Clin Oncol 22:3813–3825, 2004; Hematol Oncol Clin North Am 23:15–34, 2009). The molecular biology...

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Detalles Bibliográficos
Autores principales: Nannini, Margherita, Astolfi, Annalisa, Urbini, Milena, Indio, Valentina, Santini, Donatella, Heinrich, Michael C, Corless, Christopher L, Ceccarelli, Claudio, Saponara, Maristella, Mandrioli, Anna, Lolli, Cristian, Ercolani, Giorgio, Brandi, Giovanni, Biasco, Guido, Pantaleo, Maria A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4181714/
https://www.ncbi.nlm.nih.gov/pubmed/25239601
http://dx.doi.org/10.1186/1471-2407-14-685