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NUCKS1, a novel Tat coactivator, plays a crucial role in HIV-1 replication by increasing Tat-mediated viral transcription on the HIV-1 LTR promoter

BACKGROUND: Human immunodeficiency virus-1 (HIV-1) Tat protein plays an essential role in HIV gene transcription from the HIV-1 long terminal repeat (LTR) and replication. Transcriptional activity of Tat is modulated by several host factors, but the mechanism responsible for Tat regulation by host f...

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Detalles Bibliográficos
Autores principales: Kim, Hye-Young, Choi, Byeong-Sun, Kim, Sung Soon, Roh, Tae-Young, Park, Jihwan, Yoon, Cheol-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4181878/
https://www.ncbi.nlm.nih.gov/pubmed/25116364
http://dx.doi.org/10.1186/s12977-014-0067-y