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Chimaeric Virus-Like Particles Derived from Consensus Genome Sequences of Human Rotavirus Strains Co-Circulating in Africa

Rotavirus virus-like particles (RV-VLPs) are potential alternative non-live vaccine candidates due to their high immunogenicity. They mimic the natural conformation of native viral proteins but cannot replicate because they do not contain genomic material which makes them safe. To date, most RV-VLPs...

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Detalles Bibliográficos
Autores principales: Jere, Khuzwayo C., O'Neill, Hester G., Potgieter, A. Christiaan, van Dijk, Alberdina A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4181975/
https://www.ncbi.nlm.nih.gov/pubmed/25268783
http://dx.doi.org/10.1371/journal.pone.0105167