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Inferring Novel Indications of Approved Drugs via a Learning Method with Local and Global Consistency

Inferring new indication of approved drugs is critical not only for the elucidation of the interaction mechanisms between these drugs and their associated diseases, but also for the development of drug therapy for various human diseases. This paper proposes a network-based approach to reveal the ass...

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Detalles Bibliográficos
Autores principales: Yan, Yan, Shao, Xinwei, Jiang, Zhenran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182043/
https://www.ncbi.nlm.nih.gov/pubmed/25268268
http://dx.doi.org/10.1371/journal.pone.0107100