TGF-Beta Downregulation of Distinct Chloride Channels in Cystic Fibrosis-Affected Epithelia

RATIONALE: The cystic fibrosis transmembrane conductance regulator (CFTR) and Calcium-activated Chloride Conductance (CaCC) each play critical roles in maintaining normal hydration of epithelial surfaces including the airways and colon. TGF-beta is a genetic modifier of cystic fibrosis (CF), but how...

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Detalles Bibliográficos
Autores principales: Sun, Hongtao, Harris, William T., Kortyka, Stephanie, Kotha, Kavitha, Ostmann, Alicia J., Rezayat, Amir, Sridharan, Anusha, Sanders, Yan, Naren, Anjaparavanda P., Clancy, John P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182049/
https://www.ncbi.nlm.nih.gov/pubmed/25268501
http://dx.doi.org/10.1371/journal.pone.0106842

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182049/
https://www.ncbi.nlm.nih.gov/pubmed/25268501
http://dx.doi.org/10.1371/journal.pone.0106842

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