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TGF-Beta Downregulation of Distinct Chloride Channels in Cystic Fibrosis-Affected Epithelia

RATIONALE: The cystic fibrosis transmembrane conductance regulator (CFTR) and Calcium-activated Chloride Conductance (CaCC) each play critical roles in maintaining normal hydration of epithelial surfaces including the airways and colon. TGF-beta is a genetic modifier of cystic fibrosis (CF), but how...

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Detalles Bibliográficos
Autores principales:	Sun, Hongtao, Harris, William T., Kortyka, Stephanie, Kotha, Kavitha, Ostmann, Alicia J., Rezayat, Amir, Sridharan, Anusha, Sanders, Yan, Naren, Anjaparavanda P., Clancy, John P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182049/ https://www.ncbi.nlm.nih.gov/pubmed/25268501 http://dx.doi.org/10.1371/journal.pone.0106842

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