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PATHOME: an algorithm for accurately detecting differentially expressed subpathways

The translation of high-throughput gene expression data into biologically meaningful information remains a bottleneck. We developed a novel computational algorithm, PATHOME, for detecting differentially expressed biological pathways. This algorithm employs straightforward statistical tests to evalua...

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Detalles Bibliográficos
Autores principales: Nam, S, Chang, H R, Kim, K-T, Kook, M-C, Hong, D, Kwon, C H, Jung, H R, Park, H S, Powis, G, Liang, H, Park, T, Kim, Y H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182295/
https://www.ncbi.nlm.nih.gov/pubmed/24681952
http://dx.doi.org/10.1038/onc.2014.80