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Abnormal Calcium Handling and Exaggerated Cardiac Dysfunction in Mice with Defective Vitamin D Signaling

AIM: Altered vitamin D signaling is associated with cardiac dysfunction, but the pathogenic mechanism is not clearly understood. We examine the mechanism and the role of vitamin D signaling in the development of cardiac dysfunction. METHODS AND RESULTS: We analyzed 1α-hydroxylase (1α-OHase) knockout...

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Detalles Bibliográficos
Autores principales: Choudhury, Sangita, Bae, Soochan, Ke, Qingen, Lee, Ji Yoo, Singh, Sylvia S., St-Arnaud, René, del Monte, Federica, Kang, Peter M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182450/
https://www.ncbi.nlm.nih.gov/pubmed/25268137
http://dx.doi.org/10.1371/journal.pone.0108382