Role of Somatostatin Receptor-2 in Gentamicin-Induced Auditory Hair Cell Loss in the Mammalian Inner Ear

Hair cells and spiral ganglion neurons of the mammalian auditory system do not regenerate, and their loss leads to irreversible hearing loss. Aminoglycosides induce auditory hair cell death in vitro, and evidence suggests that phosphatidylinositol-3-kinase/Akt signaling opposes gentamicin toxicity v...

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Detalles Bibliográficos
Autores principales: Brand, Yves, Radojevic, Vesna, Sung, Michael, Wei, Eric, Setz, Cristian, Glutz, Andrea, Leitmeyer, Katharina, Bodmer, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182454/
https://www.ncbi.nlm.nih.gov/pubmed/25268135
http://dx.doi.org/10.1371/journal.pone.0108146

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182454/
https://www.ncbi.nlm.nih.gov/pubmed/25268135
http://dx.doi.org/10.1371/journal.pone.0108146

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