Phospholipase Cε, an Effector of Ras and Rap Small GTPases, Is Required for Airway Inflammatory Response in a Mouse Model of Bronchial Asthma

BACKGROUND: Phospholipase Cε (PLCε) is an effector of Ras and Rap small GTPases and expressed in non-immune cells. It is well established that PLCε plays an important role in skin inflammation, such as that elicited by phorbol ester painting or ultraviolet irradiation and contact dermatitis that is...

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Detalles Bibliográficos
Autores principales: Nagano, Tatsuya, Edamatsu, Hironori, Kobayashi, Kazuyuki, Takenaka, Nobuyuki, Yamamoto, Masatsugu, Sasaki, Naoto, Nishimura, Yoshihiro, Kataoka, Tohru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182471/
https://www.ncbi.nlm.nih.gov/pubmed/25269075
http://dx.doi.org/10.1371/journal.pone.0108373

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182471/
https://www.ncbi.nlm.nih.gov/pubmed/25269075
http://dx.doi.org/10.1371/journal.pone.0108373

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