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Phospholipase Cε, an Effector of Ras and Rap Small GTPases, Is Required for Airway Inflammatory Response in a Mouse Model of Bronchial Asthma
BACKGROUND: Phospholipase Cε (PLCε) is an effector of Ras and Rap small GTPases and expressed in non-immune cells. It is well established that PLCε plays an important role in skin inflammation, such as that elicited by phorbol ester painting or ultraviolet irradiation and contact dermatitis that is...
Autores principales: | Nagano, Tatsuya, Edamatsu, Hironori, Kobayashi, Kazuyuki, Takenaka, Nobuyuki, Yamamoto, Masatsugu, Sasaki, Naoto, Nishimura, Yoshihiro, Kataoka, Tohru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182471/ https://www.ncbi.nlm.nih.gov/pubmed/25269075 http://dx.doi.org/10.1371/journal.pone.0108373 |
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