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A Simple Extension to the CMASA Method for the Prediction of Catalytic Residues in the Presence of Single Point Mutations

The automatic identification of catalytic residues still remains an important challenge in structural bioinformatics. Sequence-based methods are good alternatives when the query shares a high percentage of identity with a well-annotated enzyme. However, when the homology is not apparent, which occur...

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Detalles Bibliográficos
Autores principales: Flores, David I., Sotelo-Mundo, Rogerio R., Brizuela, Carlos A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182483/
https://www.ncbi.nlm.nih.gov/pubmed/25268770
http://dx.doi.org/10.1371/journal.pone.0108513