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A Simple Extension to the CMASA Method for the Prediction of Catalytic Residues in the Presence of Single Point Mutations
The automatic identification of catalytic residues still remains an important challenge in structural bioinformatics. Sequence-based methods are good alternatives when the query shares a high percentage of identity with a well-annotated enzyme. However, when the homology is not apparent, which occur...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182483/ https://www.ncbi.nlm.nih.gov/pubmed/25268770 http://dx.doi.org/10.1371/journal.pone.0108513 |