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CD4(+) T Cells Expressing Latency-Associated Peptide and Foxp3 Are an Activated Subgroup of Regulatory T Cells Enriched in Patients with Colorectal Cancer
Latency-associated peptide (LAP) - expressing regulatory T cells (Tregs) are important for immunological self-tolerance and immune homeostasis. In order to investigate the role of LAP in human CD4(+)Foxp3(+) Tregs, we designed a cross-sectional study that involved 42 colorectal cancer (CRC) patients...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182495/ https://www.ncbi.nlm.nih.gov/pubmed/25268580 http://dx.doi.org/10.1371/journal.pone.0108554 |