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CD4(+) T Cells Expressing Latency-Associated Peptide and Foxp3 Are an Activated Subgroup of Regulatory T Cells Enriched in Patients with Colorectal Cancer

Latency-associated peptide (LAP) - expressing regulatory T cells (Tregs) are important for immunological self-tolerance and immune homeostasis. In order to investigate the role of LAP in human CD4(+)Foxp3(+) Tregs, we designed a cross-sectional study that involved 42 colorectal cancer (CRC) patients...

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Detalles Bibliográficos
Autores principales:	Mahalingam, Jayashri, Lin, Chun-Yen, Chiang, Jy-Ming, Su, Po-Jung, Chu, Yu-Yi, Lai, Hsin-Yi, Fang, Jian-He, Huang, Ching-Tai, Lin, Yung-Chang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182495/ https://www.ncbi.nlm.nih.gov/pubmed/25268580 http://dx.doi.org/10.1371/journal.pone.0108554

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