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The Apolipoprotein E Polymorphism rs7412 Associates with Body Fatness Independently of Plasma Lipids in Middle Aged Men

BACKGROUND: The apolipoprotein E (APOE) gene is polymorphic, encoding one of 3 common alleles (ε2, ε3, ε4) produced from combinations of 2 non-synonymous SNPs (rs429358 and rs7412). APOE plays an important role controlling plasma lipids but its association with adipocyte functionality and body fatne...

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Detalles Bibliográficos
Autores principales: Tejedor, M. Teresa, Garcia-Sobreviela, Maria Pilar, Ledesma, Marta, Arbones-Mainar, Jose M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182517/
https://www.ncbi.nlm.nih.gov/pubmed/25268647
http://dx.doi.org/10.1371/journal.pone.0108605