Prostate Tumor-Derived Exosomes Down-Regulate NKG2D Expression on Natural Killer Cells and CD8(+) T Cells: Mechanism of Immune Evasion

Tumor-derived exosomes, which are nanometer-sized extracellular vesicles of endosomal origin, have emerged as promoters of tumor immune evasion but their role in prostate cancer (PC) progression is poorly understood. In this study, we investigated the ability of prostate tumor-derived exosomes to do...

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Detalles Bibliográficos
Autores principales: Lundholm, Marie, Schröder, Mona, Nagaeva, Olga, Baranov, Vladimir, Widmark, Anders, Mincheva-Nilsson, Lucia, Wikström, Pernilla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182531/
https://www.ncbi.nlm.nih.gov/pubmed/25268476
http://dx.doi.org/10.1371/journal.pone.0108925

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182531/
https://www.ncbi.nlm.nih.gov/pubmed/25268476
http://dx.doi.org/10.1371/journal.pone.0108925

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