Sodium-Glucose Transporter-2 (SGLT2; SLC5A2) Enhances Cellular Uptake of Aminoglycosides

Aminoglycoside antibiotics, like gentamicin, continue to be clinically essential worldwide to treat life-threatening bacterial infections. Yet, the ototoxic and nephrotoxic side-effects of these drugs remain serious complications. A major site of gentamicin uptake and toxicity resides within kidney...

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Detalles Bibliográficos
Autores principales: Jiang, Meiyan, Wang, Qi, Karasawa, Takatoshi, Koo, Ja-Won, Li, Hongzhe, Steyger, Peter S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182564/
https://www.ncbi.nlm.nih.gov/pubmed/25268124
http://dx.doi.org/10.1371/journal.pone.0108941

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182564/
https://www.ncbi.nlm.nih.gov/pubmed/25268124
http://dx.doi.org/10.1371/journal.pone.0108941

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