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Soluble FGL2, a novel effector molecule of activated hepatic stellate cells, regulates T-cell function in cirrhotic patients with hepatocellular carcinoma

PURPOSE: To investigate the effects of soluble FGL2 (sFGL2) secreted by hepatic stellate cells (HSCs) on immune suppression in cirrhotic patients with hepatocellular carcinoma (HCC). METHODS: Serum sFGL2 levels were examined by ELISA in 40 patients with HCC, liver cirrhosis (LC) or chronic HBV (CHB)...

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Detalles Bibliográficos
Autores principales: Sun, Ying, Xi, Dong, Ding, Wen, Wang, Faxi, Zhou, Haili, Ning, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer India 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182595/
https://www.ncbi.nlm.nih.gov/pubmed/25298849
http://dx.doi.org/10.1007/s12072-014-9568-y