Aurora Kinases as Targets in Drug-Resistant Neuroblastoma Cells

Aurora kinase inhibitors displayed activity in pre-clinical neuroblastoma models. Here, we studied the effects of the pan-aurora kinase inhibitor tozasertib (VX680, MK-0457) and the aurora kinase inhibitor alisertib (MLN8237) that shows some specificity for aurora kinase A over aurora kinase B in a...

Descripción completa

Detalles Bibliográficos
Autores principales: Michaelis, Martin, Selt, Florian, Rothweiler, Florian, Löschmann, Nadine, Nüsse, Benedikt, Dirks, Wilhelm G., Zehner, Richard, Cinatl, Jindrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182628/
https://www.ncbi.nlm.nih.gov/pubmed/25268132
http://dx.doi.org/10.1371/journal.pone.0108758

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182628/
https://www.ncbi.nlm.nih.gov/pubmed/25268132
http://dx.doi.org/10.1371/journal.pone.0108758

Ejemplares similares