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Aurora Kinases as Targets in Drug-Resistant Neuroblastoma Cells

Aurora kinase inhibitors displayed activity in pre-clinical neuroblastoma models. Here, we studied the effects of the pan-aurora kinase inhibitor tozasertib (VX680, MK-0457) and the aurora kinase inhibitor alisertib (MLN8237) that shows some specificity for aurora kinase A over aurora kinase B in a...

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Detalles Bibliográficos
Autores principales:	Michaelis, Martin, Selt, Florian, Rothweiler, Florian, Löschmann, Nadine, Nüsse, Benedikt, Dirks, Wilhelm G., Zehner, Richard, Cinatl, Jindrich
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182628/ https://www.ncbi.nlm.nih.gov/pubmed/25268132 http://dx.doi.org/10.1371/journal.pone.0108758

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