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The Actin-Sequestering Protein Thymosin Beta-4 Is a Novel Target of Hypoxia-Inducible Nitric Oxide and HIF-1α Regulation

The actin-sequestering protein thymosin beta-4 (Tβ4) is involved in various cellular and physiological processes such as proliferation, motility, growth and metastasis. Nitric oxide (NO) promotes tumor invasiveness and metastasis by activating various enzymes. Herein, we investigated whether hypoxia...

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Detalles Bibliográficos
Autores principales: Ryu, Yun-Kyoung, Kang, Joo-Hyun, Moon, Eun-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182666/
https://www.ncbi.nlm.nih.gov/pubmed/25271630
http://dx.doi.org/10.1371/journal.pone.0106532