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Biological and Molecular Effects of Small Molecule Kinase Inhibitors on Low-Passage Human Colorectal Cancer Cell Lines

Low-passage cancer cell lines are versatile tools to study tumor cell biology. Here, we have employed four such cell lines, established from primary tumors of colorectal cancer (CRC) patients, to evaluate effects of the small molecule kinase inhibitors (SMI) vemurafenib, trametinib, perifosine, and...

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Detalles Bibliográficos
Autores principales: Lange, Falko, Franz, Benjamin, Maletzki, Claudia, Linnebacher, Michael, Hühns, Maja, Jaster, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182691/
https://www.ncbi.nlm.nih.gov/pubmed/25309914
http://dx.doi.org/10.1155/2014/568693