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Lenalidomide Induces Immunomodulation in Chronic Lymphocytic Leukemia and Enhances Antitumor Immune Responses Mediated by NK and CD4 T Cells

Lenalidomide is an immunomodulatory drug with therapeutic activity in chronic lymphocytic leukemia (CLL). However, it has pleiotropic effects, and the mechanism of action responsible for its therapeutic activity has not been well defined yet. Herein, we show that lenalidomide treatment does not have...

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Detalles Bibliográficos
Autores principales: Acebes-Huerta, Andrea, Huergo-Zapico, Leticia, Gonzalez-Rodriguez, Ana Pilar, Fernandez-Guizan, Azahara, Payer, Angel R., López-Soto, Alejandro, Gonzalez, Segundo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182694/
https://www.ncbi.nlm.nih.gov/pubmed/25313353
http://dx.doi.org/10.1155/2014/265840