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Interruption of Wnt Signaling in Müller Cells Ameliorates Ischemia-Induced Retinal Neovascularization

Retinal Müller cells are major producers of inflammatory and angiogenic cytokines which contribute to diabetic retinopathy (DR). Over-activation of the Wnt/β-catenin pathway has been shown to play an important pathogenic role in DR. However, the roles of Müller cell-derived Wnt/β-catenin signaling i...

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Detalles Bibliográficos
Autores principales: Zhou, Kelu Kevin, Benyajati, Siribhinya, Le, Yun, Cheng, Rui, Zhang, Wenbo, Ma, Jian-xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182699/
https://www.ncbi.nlm.nih.gov/pubmed/25271989
http://dx.doi.org/10.1371/journal.pone.0108454