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Adenosine Deaminase Acting on RNA-1 (ADAR1) Inhibits HIV-1 Replication in Human Alveolar Macrophages

While exploring the effects of aerosol IFN-γ treatment in HIV-1/tuberculosis co-infected patients, we observed A to G mutations in HIV-1 envelope sequences derived from bronchoalveolar lavage (BAL) of aerosol IFN-γ-treated patients and induction of adenosine deaminase acting on RNA 1 (ADAR1) in the...

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Detalles Bibliográficos
Autores principales: Weiden, Michael D., Hoshino, Satomi, Levy, David N., Li, Yonghua, Kumar, Rajnish, Burke, Sean A., Dawson, Rodney, Hioe, Catarina E., Borkowsky, William, Rom, William N., Hoshino, Yoshihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182706/
https://www.ncbi.nlm.nih.gov/pubmed/25272020
http://dx.doi.org/10.1371/journal.pone.0108476