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Association between Polymorphisms of the IKZF3 Gene and Systemic Lupus Erythematosus in a Chinese Han Population

OBJECTIVE: It has been reported that IKAROS family of zinc finger 3 (IKZF3)-deficient mice spontaneously develop human systemic lupus erythematosus (SLE)-like phenotypes and produce anti-dsDNA Ab leading to immune complex-mediated glomerulonephritis. Polymorphism of the IKZF3 gene corresponds with t...

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Detalles Bibliográficos
Autores principales: Cai, Xinze, Qiao, Ying, Diao, Cheng, Xu, Xiaoxue, Chen, Yang, Du, Shuyan, Liu, Xudong, Liu, Nan, Yu, Shuang, Chen, Dong, Jiang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182708/
https://www.ncbi.nlm.nih.gov/pubmed/25271777
http://dx.doi.org/10.1371/journal.pone.0108661