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The impact of single and pairwise Toll-like receptor activation on neuroinflammation and neurodegeneration
BACKGROUND: Toll-like receptors (TLRs) enable innate immune cells to respond to pathogen- and host-derived molecules. The central nervous system (CNS) exhibits most of the TLRs identified with predominant expression in microglia, the major immune cells of the brain. Although individual TLRs have bee...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182775/ https://www.ncbi.nlm.nih.gov/pubmed/25239168 http://dx.doi.org/10.1186/s12974-014-0166-7 |