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The impact of single and pairwise Toll-like receptor activation on neuroinflammation and neurodegeneration

BACKGROUND: Toll-like receptors (TLRs) enable innate immune cells to respond to pathogen- and host-derived molecules. The central nervous system (CNS) exhibits most of the TLRs identified with predominant expression in microglia, the major immune cells of the brain. Although individual TLRs have bee...

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Detalles Bibliográficos
Autores principales:	Rosenberger, Karen, Derkow, Katja, Dembny, Paul, Krüger, Christina, Schott, Eckart, Lehnardt, Seija
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182775/ https://www.ncbi.nlm.nih.gov/pubmed/25239168 http://dx.doi.org/10.1186/s12974-014-0166-7

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