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Pre- and Postovulatory Aging of Murine Oocytes Affect the Transcript Level and Poly(A) Tail Length of Maternal Effect Genes

Maternal effect genes code for oocyte proteins that are important for early embryogenesis. Transcription in oocytes does not take place from the onset of meiotic progression until zygotic genome activation. During this period, protein levels are regulated posttranscriptionally, for example by poly(A...

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Detalles Bibliográficos
Autores principales: Dankert, Debora, Demond, Hannah, Trapphoff, Tom, Heiligentag, Martyna, Rademacher, Katrin, Eichenlaub-Ritter, Ursula, Horsthemke, Bernhard, Grümmer, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182777/
https://www.ncbi.nlm.nih.gov/pubmed/25271735
http://dx.doi.org/10.1371/journal.pone.0108907