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BosR Functions as a Repressor of the ospAB Operon in Borrelia burgdorferi

The Lyme disease spirochete, Borrelia burgdorferi, must abundantly produce outer surface lipoprotein A (OspA) in the tick vector but downregulate OspA in mammals in order to evade the immune system and maintain its natural enzootic cycle. Here, we show that BosR binds two regulatory elements of the...

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Detalles Bibliográficos
Autores principales: Shi, Yanlin, Dadhwal, Poonam, Li, Xin, Liang, Fang Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182837/
https://www.ncbi.nlm.nih.gov/pubmed/25271631
http://dx.doi.org/10.1371/journal.pone.0109307