Androgen Suppresses the Proliferation of Androgen Receptor-Positive Castration-Resistant Prostate Cancer Cells via Inhibition of Cdk2, CyclinA, and Skp2

The majority of prostate cancer (PCa) patient receiving androgen ablation therapy eventually develop castration-resistant prostate cancer (CRPC). We previously reported that androgen treatment suppresses Skp2 and c-Myc through androgen receptor (AR) and induced G1 cell cycle arrest in androgen-indep...

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Detalles Bibliográficos
Autores principales: Kokontis, John M., Lin, Hui-Ping, Jiang, Shih Sheng, Lin, Ching-Yu, Fukuchi, Junichi, Hiipakka, Richard A., Chung, Chi-Jung, Chan, Tzu-Min, Liao, Shutsung, Chang, Chung-Ho, Chuu, Chih-Pin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182885/
https://www.ncbi.nlm.nih.gov/pubmed/25271736
http://dx.doi.org/10.1371/journal.pone.0109170

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182885/
https://www.ncbi.nlm.nih.gov/pubmed/25271736
http://dx.doi.org/10.1371/journal.pone.0109170

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