Cardiac-targeting magnetic lipoplex delivery of SH-IGF1R plasmid attenuate norepinephrine-induced cardiac hypertrophy in murine heart

Recent studies have demonstrated a number of molecular mechanisms contributing to the initiation of cardiac hypertrophy response to pressure overload. IGF1R (insulin-like growth factor-1 receptor), an important oncogene, is overexpressed in hypertrophic heart and mediates the hypertrophic pathology...

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Detalles Bibliográficos
Autores principales: Xu, Yiping, Li, Xuebiao, Kong, Minjian, Jiang, Daming, Dong, Aiqiang, Shen, Zhonghua, Duan, Qunjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2014
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182904/
https://www.ncbi.nlm.nih.gov/pubmed/24965872
http://dx.doi.org/10.1042/BSR20130107

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182904/
https://www.ncbi.nlm.nih.gov/pubmed/24965872
http://dx.doi.org/10.1042/BSR20130107

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