Distinct Pathways Mediate Axon Degeneration during Apoptosis and Axon-Specific Pruning

Neurons can activate pathways that destroy the whole cell via apoptosis or selectively degenerate only the axon (pruning). Both apoptosis and axon degeneration require Bax and caspases. Here we demonstrate that despite this overlap, the pathways mediating axon degeneration during apoptosis versus ax...

Descripción completa

Detalles Bibliográficos
Autores principales: Cusack, Corey L., Swahari, Vijay, Henley, W. Hampton, Ramsey, J. Michael, Deshmukh, Mohanish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183061/
https://www.ncbi.nlm.nih.gov/pubmed/23695670
http://dx.doi.org/10.1038/ncomms2910

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183061/
https://www.ncbi.nlm.nih.gov/pubmed/23695670
http://dx.doi.org/10.1038/ncomms2910

Ejemplares similares