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Spontaneous locomotor activity and L-DOPA-induced dyskinesia are not linked in 6-OHDA parkinsonian rats

Bradykinesia (slowness of movement) and other characteristic motor manifestations of Parkinson’s disease (PD) are alleviated by treatment with L-dihydroxyphenylalanine (L-DOPA). Long-term L-DOPA treatment, however, is associated with complications such as motor fluctuations and dyskinesia that sever...

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Detalles Bibliográficos
Autores principales: Sgroi, Stefania, Kaelin-Lang, Alain, Capper-Loup, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183109/
https://www.ncbi.nlm.nih.gov/pubmed/25324746
http://dx.doi.org/10.3389/fnbeh.2014.00331