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Hamiltonian Mapping Revisited: Calibrating Minimalist Models to Capture Molecular Recognition by Intrinsically Disordered Proteins

[Image: see text] Molecular recognition by intrinsically disordered proteins (IDPs) plays a central role in many critical cellular processes. Toward achieving detailed mechanistic understanding of IDP–target interactions, here we employ the “Hamiltonian mapping” methodology, which is rooted in the w...

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Detalles Bibliográficos
Autores principales: Law, Sean M., Ahlstrom, Logan S., Panahi, Afra, Brooks, Charles L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183358/
https://www.ncbi.nlm.nih.gov/pubmed/25289116
http://dx.doi.org/10.1021/jz501811k