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Hamiltonian Mapping Revisited: Calibrating Minimalist Models to Capture Molecular Recognition by Intrinsically Disordered Proteins
[Image: see text] Molecular recognition by intrinsically disordered proteins (IDPs) plays a central role in many critical cellular processes. Toward achieving detailed mechanistic understanding of IDP–target interactions, here we employ the “Hamiltonian mapping” methodology, which is rooted in the w...
Autores principales: | Law, Sean M., Ahlstrom, Logan S., Panahi, Afra, Brooks, Charles L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183358/ https://www.ncbi.nlm.nih.gov/pubmed/25289116 http://dx.doi.org/10.1021/jz501811k |
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