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Dark-Field Illumination on Zero-Mode Waveguide/Microfluidic Hybrid Chip Reveals T4 Replisomal Protein Interactions

[Image: see text] The ability of zero-mode waveguides (ZMWs) to guide light energy into subwavelength-diameter cylindrical nanoapertures has been exploited for single-molecule fluorescence studies of biomolecules at micromolar concentrations, the typical dissociation constants for biomolecular inter...

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Detalles Bibliográficos
Autores principales: Zhao, Yanhui, Chen, Danqi, Yue, Hongjun, Spiering, Michelle M., Zhao, Chenglong, Benkovic, Stephen J., Huang, Tony Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183369/
https://www.ncbi.nlm.nih.gov/pubmed/24628474
http://dx.doi.org/10.1021/nl404802f