Cargando…

H2B Mono-ubiquitylation Facilitates Fork Stalling and Recovery during Replication Stress by Coordinating Rad53 Activation and Chromatin Assembly

The influence of mono-ubiquitylation of histone H2B (H2Bub) on transcription via nucleosome reassembly has been widely documented. Recently, it has also been shown that H2Bub promotes recovery from replication stress; however, the underling molecular mechanism remains unclear. Here, we show that H2B...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, Chia-Yeh, Wu, Meng-Ying, Gay, Sophie, Marjavaara, Lisette, Lai, Mong Sing, Hsiao, Wei-Chun, Hung, Shih-Hsun, Tseng, Hsin-Yi, Wright, Duncan Edward, Wang, Chen-Yi, Hsu, Guoo-Shyng W., Devys, Didier, Chabes, Andrei, Kao, Cheng-Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183429/
https://www.ncbi.nlm.nih.gov/pubmed/25275495
http://dx.doi.org/10.1371/journal.pgen.1004667