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JAK2/STAT3 Inhibition Attenuates Noise-Induced Hearing Loss

Signal transducers and activators of transcription 3 (STAT3) is a stress responsive transcription factor that plays a key role in oxidative stress-mediated tissue injury. As reactive oxygen species (ROS) are a known source of damage to tissues of the inner ear following loud sound exposure, we exami...

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Detalles Bibliográficos
Autores principales: Wilson, Teresa, Omelchenko, Irina, Foster, Sarah, Zhang, Yuan, Shi, Xiaorui, Nuttall, Alfred L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183445/
https://www.ncbi.nlm.nih.gov/pubmed/25275304
http://dx.doi.org/10.1371/journal.pone.0108276