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JAK2/STAT3 Inhibition Attenuates Noise-Induced Hearing Loss
Signal transducers and activators of transcription 3 (STAT3) is a stress responsive transcription factor that plays a key role in oxidative stress-mediated tissue injury. As reactive oxygen species (ROS) are a known source of damage to tissues of the inner ear following loud sound exposure, we exami...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183445/ https://www.ncbi.nlm.nih.gov/pubmed/25275304 http://dx.doi.org/10.1371/journal.pone.0108276 |