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Brugia malayi Microfilariae Induce a Regulatory Monocyte/Macrophage Phenotype That Suppresses Innate and Adaptive Immune Responses

BACKGROUND: Monocytes and macrophages contribute to the dysfunction of immune responses in human filariasis. During patent infection monocytes encounter microfilariae in the blood, an event that occurs in asymptomatically infected filariasis patients that are immunologically hyporeactive. AIM: To de...

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Detalles Bibliográficos
Autores principales: O'Regan, Noëlle Louise, Steinfelder, Svenja, Venugopal, Gopinath, Rao, Gopala B., Lucius, Richard, Srikantam, Aparna, Hartmann, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183501/
https://www.ncbi.nlm.nih.gov/pubmed/25275395
http://dx.doi.org/10.1371/journal.pntd.0003206