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Brugia malayi Microfilariae Induce a Regulatory Monocyte/Macrophage Phenotype That Suppresses Innate and Adaptive Immune Responses
BACKGROUND: Monocytes and macrophages contribute to the dysfunction of immune responses in human filariasis. During patent infection monocytes encounter microfilariae in the blood, an event that occurs in asymptomatically infected filariasis patients that are immunologically hyporeactive. AIM: To de...
Autores principales: | O'Regan, Noëlle Louise, Steinfelder, Svenja, Venugopal, Gopinath, Rao, Gopala B., Lucius, Richard, Srikantam, Aparna, Hartmann, Susanne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183501/ https://www.ncbi.nlm.nih.gov/pubmed/25275395 http://dx.doi.org/10.1371/journal.pntd.0003206 |
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