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Cannabinoids Alleviate Experimentally Induced Intestinal Inflammation by Acting at Central and Peripheral Receptors

BACKGROUND AND AIMS: In an attempt to further investigate the role of cannabinoid (CB) system in the pathogenesis of inflammatory bowel diseases, we employed two recently developed ligands, AM841 (a covalently acting CB agonist) and CB13 (a peripherally-restricted CB agonist) to establish whether ce...

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Detalles Bibliográficos
Autores principales: Fichna, Jakub, Bawa, Misha, Thakur, Ganesh A., Tichkule, Ritesh, Makriyannis, Alexandros, McCafferty, Donna-Marie, Sharkey, Keith A., Storr, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183544/
https://www.ncbi.nlm.nih.gov/pubmed/25275313
http://dx.doi.org/10.1371/journal.pone.0109115