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EGFR has a tumor-promoting role in liver macrophages during hepatocellular carcinoma formation

Hepatocellular carcinoma (HCC) is a frequent cancer with limited treatment options and poor prognosis. Tumorigenesis has been linked with macrophage-mediated chronic inflammation and diverse signaling pathways including the Epidermal Growth Factor Receptor (EGFR) pathway. The precise role of EGFR in...

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Detalles Bibliográficos
Autores principales: Lanaya, Hanane, Natarajan, Anuradha, Komposch, Karin, Li, Liang, Amberg, Nicole, Chen, Lei, Wculek, Stefanie K., Hammer, Martina, Zenz, Rainer, Peck-Radosavljevic, Markus, Sieghart, Wolfgang, Trauner, Michael, Wang, Hongyang, Sibilia, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183558/
https://www.ncbi.nlm.nih.gov/pubmed/25173978
http://dx.doi.org/10.1038/ncb3031