Systematic characterization of deubiquitylating enzymes for roles in maintaining genome integrity

DNA double-strand breaks (DSBs) are perhaps the most toxic of all DNA lesions, with defects in the DNA damage response to DSBs being associated with various human diseases. Although it is known that DSB repair pathways are tightly regulated by ubiquitylation, we do not yet have a comprehensive under...

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Detalles Bibliográficos
Autores principales: Nishi, Ryotaro, Wijnhoven, Paul, le Sage, Carlos, Tjeertes, Jorrit, Galanty, Yaron, Forment, Josep V., Clague, Michael J., Urbé, Sylvie, Jackson, Stephen P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183562/
https://www.ncbi.nlm.nih.gov/pubmed/25194926
http://dx.doi.org/10.1038/ncb3028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183562/
https://www.ncbi.nlm.nih.gov/pubmed/25194926
http://dx.doi.org/10.1038/ncb3028

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