Cyclophilin A Associates with Enterovirus-71 Virus Capsid and Plays an Essential Role in Viral Infection as an Uncoating Regulator

Viruses utilize host factors for their efficient proliferation. By evaluating the inhibitory effects of compounds in our library, we identified inhibitors of cyclophilin A (CypA), a known immunosuppressor with peptidyl-prolyl cis-trans isomerase activity, can significantly attenuate EV71 proliferati...

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Detalles Bibliográficos
Autores principales: Qing, Jie, Wang, Yaxin, Sun, Yuna, Huang, Jiaoyan, Yan, Wenzhong, Wang, Jinglan, Su, Dan, Ni, Cheng, Li, Jian, Rao, Zihe, Liu, Lei, Lou, Zhiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183573/
https://www.ncbi.nlm.nih.gov/pubmed/25275585
http://dx.doi.org/10.1371/journal.ppat.1004422

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183573/
https://www.ncbi.nlm.nih.gov/pubmed/25275585
http://dx.doi.org/10.1371/journal.ppat.1004422

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