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IL-32γ Delays Spontaneous Apoptosis of Human Neutrophils through MCL-1, Regulated Primarily by the p38 MAPK Pathway

IL-32γ is a multifunctional cytokine involved in various inflammatory and auto-immune diseases in which neutrophils can affect the evolution of these diseases. To persist at inflammatory sites, neutrophils require inhibition of their rapid and constitutive apoptosis, an inhibitory effect that phlogo...

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Detalles Bibliográficos
Autores principales: Allaeys, Isabelle, Gymninova, Irina, Canet-Jourdan, Charlotte, Poubelle, Patrice E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183585/
https://www.ncbi.nlm.nih.gov/pubmed/25275312
http://dx.doi.org/10.1371/journal.pone.0109256