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Ligand-Promoted Alkylation of C(sp(3))–H and C(sp(2))–H Bonds
[Image: see text] 9-Methylacridine was identified as a generally effective ligand to promote a Pd(II)-catalyzed C(sp(3))–H and C(sp(2))–H alkylation of simple amides with various alkyl iodides. This alkylation reaction was applied to the preparation of unnatural amino acids and geometrically control...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183600/ https://www.ncbi.nlm.nih.gov/pubmed/25208210 http://dx.doi.org/10.1021/ja508165a |