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Crystal Structure Studies of RNA Duplexes Containing s(2)U:A and s(2)U:U Base Pairs

[Image: see text] Structural studies of modified nucleobases in RNA duplexes are critical for developing a full understanding of the stability and specificity of RNA base pairing. 2-Thio-uridine (s(2)U) is a modified nucleobase found in certain tRNAs. Thermodynamic studies have evaluated the effects...

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Detalles Bibliográficos
Autores principales: Sheng, Jia, Larsen, Aaron, Heuberger, Benjamin D., Blain, J. Craig, Szostak, Jack W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183603/
https://www.ncbi.nlm.nih.gov/pubmed/25188906
http://dx.doi.org/10.1021/ja508015a